منابع مشابه
Influence of Dietary Protein and Vitamin B12on the Toxicity and Carcinogenicity of Aflatoxins in Rat Liver1
The influence of dietary protein content and dietary vitamin B,, supplement on the hepatotoxicity and carcinogenicity of aflatoxin in rat liver was studied. In animals fed a low-protein diet, aflatoxin induced extensive toxic and carcinogenic effects. Cirrhosis was significantly pre vented to a certain level by vitamin B,_administration, but the incidence of cholangiofibrosis and hyperplastic n...
متن کاملStructure-Activity Relationships in Toxicity and Carcinogenicity of Aflatoxins and Analogs1
Aflatoxins B! and G,, in single doses, were lethal and had similar relative potencies in the duckling (50% lethal dose, 0.73 mg/kg versus 1.18 mg/kg) and in the rat (50% lethal dose, 1.16 mg/kg versus 2 to 4 mg/kg). Aflatoxins B2 and G2 were less potent in the duckling (50% lethal dose, 1.76 mg/kg versus 2.83 mg/kg) and were nontoxic to rats at doses of 200 mg/kg. Aflatoxin BI induced hepatocel...
متن کاملStructure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs.
Aflatoxins B! and G,, in single doses, were lethal and had similar relative potencies in the duckling (50% lethal dose, 0.73 mg/kg versus 1.18 mg/kg) and in the rat (50% lethal dose, 1.16 mg/kg versus 2 to 4 mg/kg). Aflatoxins B2 and G2 were less potent in the duckling (50% lethal dose, 1.76 mg/kg versus 2.83 mg/kg) and were nontoxic to rats at doses of 200 mg/kg. Aflatoxin BI induced hepatocel...
متن کاملModelling the dynamics of toxicity associated with aflatoxins in foods and feeds
In this paper, we developed a mathematical model to describethe dynamics of Aflatoxins in plants, animals, and humans. Fourequilibrium points were found, and their stability analyses wereconducted using threshold quantities. If both are less than one, thestandardized toxic limit is not exceeded, while if both are greater thanone it is exceeded in both animals and humans. Standardized toxic limi...
متن کاملEffect of some Strains of Probiotic Bacteria against Toxicity Induced by Aflatoxins in vivo
Aflatoxins are highly toxic, mutagenic, teratogenic and carcinogenic compounds produced by some species of Aspergillus, especially A. flavus and A. parasiticus. This study was conducted investigate the effect of some strains of probiotic bacteria against toxicity induced by contaminated diet with aflatoxins in male rats. Animals were divided into 6 equal groups each group contains 7 rats. The f...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1971
ISSN: 0306-3283
DOI: 10.1042/bj1250019pb